Professor Martin Lavin
Research Interests
The major focus of Professor Lavin's research has been on the
importance of DNA damage response in minimising genetic instability
and cancer. He has also stablished an international reputation for
my work on the human genetic disorder ataxia-telangiectasia.
Professor Lavin's research interests included cancer genetics;
neurodegenerative disease; early detection of prostate cancer and
evaluation of snake venom proteins with therapeutic potential.
Research Projects
Pre-clinical evaluation of snake venom proteins with therapeutic
potential, 2008 - 2011
Funded by: Australian Research Council, University Of Queensland,
Venomics Pty Limited
Characterisation of the novel mitochondrial protein
(CABC1/ADCK3) and its role in protecting against oxidative stress.
(DP1092466) (2008 - 2010). Funded by Australian Research
Council
To investigate the role of the protein kinase SMG-1 in the
stress response (DP1092489) (2008 - 2010). Funded by Australian
Research Council
The relationship between PCA3 and BMCC1 in prostate cancer
development and detection (2009 - 2011). Funded by Prostate Cancer
Foundation
Role of Senataxin in protecting against neurodegeneration (Ref
631425) (2010 - 2012). Funded by NHMRC
Rad50 protects the integrity of the genome to minimise disease
risk (Ref 631425). Funded by NHMRC
ATM Activation and its functional importance in DNA damage
response (Ref 569591). Funded by NHMRC
Funding Acknowledgement
NHMRC, ARC, BrAshAT Foundation
Collaborations
Dr Georgia Chenevix-Trench
Dr
Raymond Clarke
Professor Robert Gardiner, AM
Professor Philip Robinsen
Associate
Professor Luke Guddat
Dr
Kumkum Khanna
Dr Paul Masci
Dr Gisela Tanchor-Scholz
GSI Helmholtzentrum
Darmstadt Germany
Dr Thilo Dork
Hannover Medical School
Germany
Professor
Robert Parton
Tanya Paull
University of Texas at Austin
Dr Hemamali Samaratunga
Dr Jorg Heierhorst
St Vincents Institute of Medical Research
Melbourne
Research Staff
Postdoctoral Staff: Sergei Kozlov, Olivier
Becherel, Magtouf Gatei, Amanda Wraith Kijas, Renee Stirling,
Kongnan Zhao, Misook Kim, Jason Cullen, Tara Roberts, Uda Ho
Research assistants: Aine Farrel, John Luff
Students: Shazrul Fazry, Marion Buck, Linda
Teng, Abrey Yeo, Hazel Quek, Evelyn Heng, Romal Stewart, Yi
Lim
Key Words
Genetic disorders, Neurodegeneration,
Ataxia-Telangiectasia, Prostate cancer, Snake venom
proteins
