Professor David Paterson
Email: d.paterson1@uq.edu.au
David L Paterson is a Professor of Medicine at the University of Queensland Centre for Clinical Research (UQCCR). He is also an Infectious Diseases Physician, Consultant Microbiologist and Medical Advisor for the Centre for Healthcare Related Infection Prevention and Surveillance (CHRISP).
Professor Paterson is a Brisbane trained Infectious Disease Physician whose clinical work, research and teaching has been honoured and recognised internationally. He received both his medical degree and PhD from the University of Queensland. In 2007, Professor Paterson returned to Brisbane after spending ten years at the University of Pittsburgh School of Medicine, one of the leading academic medical institutions in the U.S. His work at the University of Pittsburgh Medical Center included appointments as Chief of Transplant Infectious Disease and Director of the Antibiotic Management Program. In 2000 he was one of two recipients of the prestigious American Society for Microbiology's (ASM) Merck Irving Sigal Memorial Award for "Significant Research in Microbiology and Infectious Diseases". He has received the 2008 Frank Fenner Award for Advanced Research in Infectious Diseases by the Australasian Society for Infectious Diseases and in 2009 was winner of a Queensland Health Senior Clinical Research Fellowship.
Professor Paterson is the author of more than 175 peer-reviewed publications, of which nearly half have been published in the last three years. He has authored more than 20 book chapters and is a member of the editorial board of two leading infectious diseases journals. He is a regularly invited to speak at leading national and international conferences and has lectured in 26 different countries.
His research interest includes study of the molecular and clinical epidemiology of infections with antibiotic resistant organisms. This focus of this work is the translation of knowledge into optimal prevention and treatment of these infections. Professor Paterson has received research funding from the Centers for Disease Control and Prevention (CDC) and the National Health and Medical Research Council (NHMRC).
Professor Paterson has mentored a number of prominent emerging leaders in the field of Infectious Diseases. These include Anton Y. Peleg MBBS, FRACP (2009 winner of the American Society for Microbiology's (ASM) Merck Irving Sigal Memorial Award), Yohei Doi MD, PhD and Fernanda Silveira MD (both Assistant Professors, University of Pittsburgh Medical Center).
Professor Paterson's research laboratory is led by Hanna Sidjabat PhD.
Research Projects
Key publicationsMuto, C. A., M. K. Blank, J. W. Marsh, E. N. Vergis, M. M. O'Leary, K. A. Shutt, A. W. Pasculle, M. Pokrywka, J. G. Garcia, K. Posey, T. L. Roberts, B. A. Potoski, G. E. Blank, R. L. Simmons, P. Veldkamp, L. H. Harrison, and D. L. Paterson. 2007. Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach. Clin Infect Dis 45:1266-73. Paterson, D. L., W. C. Ko, A. Von Gottberg, S. Mohapatra, J. M. Casellas, H. Goossens, L. Mulazimoglu, G. Trenholme, K. P. Klugman, R. A. Bonomo, L. B. Rice, M. M. Wagener, J. G. McCormack, and V. L. Yu. 2004. International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections. Ann Intern Med 140:26-32. Paterson, D. L., S. Swindells, J. Mohr, M. Brester, E. N. Vergis, C. Squier, M. M. Wagener, and N. Singh. 2000. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 133:21-30. ReviewsAbrahamian, F. M., P. M. Deblieux, C. L. Emerman, M. H. Kollef, E. Kupersmith, K. V. Leeper, Jr., D. L. Paterson, and A. F. Shorr. 2008. Health care-associated pneumonia: identification and initial management in the ED. Am J Emerg Med 26:1-11. IF: 1.164 Kollef, M. H., L. E. Morrow, R. P. Baughman, D. E. Craven, J. E. McGowan, Jr., S. T. Micek, M. S. Niederman, D. Ost, D. L. Paterson, and J. Segreti. 2008. Health care-associated pneumonia (HCAP): a critical appraisal to improve identification, management, and outcomes--proceedings of the HCAP Summit. Clin Infect Dis 46 Suppl 4:S296-334; quiz 335-8. IF: 6.750 Paterson, D. L. 2008. Impact of antibiotic resistance in gram-negative bacilli on empirical and definitive antibiotic therapy. Clin Infect Dis 47 Suppl 1:S14-20. IF: 6.750 Other PublicationsEditorials in peer-reviewed journals Paterson, D. L. 2008. The molecular epidemiology of extended-spectrum beta-lactamase producing organisms. Enferm Infecc Microbiol Clin 26:403. IF: 1.096 |
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Potential PhD ProjectsA number of potential PhD project are available on the following topics
Contact details and emailThe University of Queensland Centre for Clinical Research (UQCCR) PROFESSOR OF MEDICINE David L. Paterson The University of Queensland, Building 71/918 RBWH Herston QLD 4029 Telephone: (07) 3346 6074 Facsimile: (07) 3346 5598 Email: d.paterson1@uq.edu.au |
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Group MembersDr Hisashi Baba MD PhD FJSIM JRS, Visiting Academic UQCCR Dr Yoshiro Hayashi MD PhD JSA JSICM, Visiting Academic UQCCR Dr Abdullah Fatimah Haslina, Visiting Academic UQCCR Dr Ahmad Rahman, Visiting Academic UQCCR |
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Funding acknowledgementProfessor Paterson was Principal Investigator on a major grant from the National Institutes of Health (budget $US3.4 million) for the project "Optimizing dosing of colistin for infections resistant to all other antibiotics". Additionally, two significant grants have been received from the Centers for Disease Control and Prevention: "Organ transplant infection prevention"; and "Validation of National Committee for Clinical Laboratory Standards Breakpoints for Organisms of Public Health Importance". Professor Paterson is currently a Chief Investigator on two project grants from the NHMRC: "Predicting the risk of invasive candidiasis in critically ill patients"; and: "Antibiotic dosing in the 'at risk' critically ill patient". |
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CollaborationsInternationalUniversity of Pittsburgh School of MedicineDr Fernanda Silveira and Dr John Kellum Pharmacokinetics of colistin NIH grant "Optimizing dosing of colistin for infections resistant to all other antibiotics". Joint publications: 11 Dr Yohei Doi Newer beta-lactamases Grant : AstraZeneca "Gram negative bacteremia" Joint publications : 17 Harvard UniversityDr Anton Peleg Acinetobacter infections Joint publications : 10 University of ColoradoDr Douglas Fish Pharmacokinetics of colistin NIH grant "Optimizing dosing of colistin for infections resistant to all other antibiotics". University at BuffaloDr Alan Forrest Pharmacokinetics of colistin NIH grant "Optimizing dosing of colistin for infections resistant to all other antibiotics". Centers for Disease Control and PreventionDrs Tom Chiller, Ben Park and Scott Fridkin Infections in transplant recipients CDC grant "Organ transplant infection prevention" University of AlabamaDr Pete Pappas Infections in transplant recipients CDC grant "Organ transplant infection prevention" The Cleveland Clinic FoundationDrs Robyn Avery and Steve Gordon Infections in transplant recipients CDC grant "Organ transplant infection prevention" Case Western Reserve UniversityDrs Robert Bonomo, Louis Rice and Curtis Donskey Newer beta-lactamases CDC grant: Validation of National Committee for Clinical Laboratory Standards Breakpoints for Organisms of Public Health Importance Joint publications: 18 Mahidol University, BangkokDr Visanu Thamlikitkul Pharmacokinetics of colistin NIH grant "Optimizing dosing of colistin for infections resistant to all other antibiotics". Hospital Universitario Virgen Macarena, Seville, SpainDrs Jesus Rodriguez-Bano and Pilar Retamar Newer beta-lactamases Joint publication: 2 Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, GermanyDr Harald Seifert Acinetobacter infections Joint publication: 1 Semmelweis University, Budapest, HungaryDr Dora Szabo Newer beta-lactamases Joint publications: 9 NationalProf. Roger NationMonash University Pharmacokinetics of colistin NIH grant "Optimizing dosing of colistin for infections resistant to all other antibiotics". Joint publication: 1 Prof. Tania SorrellUniversity of Sydney Infections in the critically ill NHMRC grant: Predicting the risk of invasive candidiasis in critically ill patients. Prof. Jeffrey LipmanThe University of Queensland Infections in the critically ill NHMRC grant: "Antibiotic dosing in the "at risk" critically ill patient". Joint publications: 2 Dr Mark SchembriThe University of Queensland Acinetobacter infections NHMRC Proposal. Understanding the Acinetobacter genome. Dr Scott BeatsonThe University of Queensland Acinetobacter infections NHMRC Proposal. Understanding the Acinetobacter genome. Dr Matthew CooperThe University of Queensland Development of new antibiotics NHMRC proposal. Semi-synthetic derivatives of vancomycin and colistin |
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