Hosam Zowawi

Contact Details

Infection and Immunity theme
UQ Centre for Clinical Research, The University of Queensland
Building 71/918, Royal Brisbane and women's Hospital Campus, 
Herston, QLD, 4029, Australia

T +61-7-334-660-81
M +61-431-021-166
E h(dot)zowawi(at)uq(dot)edu(dot)au    

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Research Interests

Hosam Zowawi is interested in hospital-acquired infections, particularly those caused by antimicrobial resistant organisms. As a clinical microbiologist he recognized the need to develop more rapid diagnostic tools to aid initial medical management and implement infection control precautions. Hosam is also passionate about health promotion to raise public and medical awareness about antimicrobial resistance.

He completed a Masters degree in Clinical Science (Clinical Microbiology) with Honours and received the Griffith University Award for Academic Excellence 2010. In his master's dissertation he studied catheter-related infections (CRIs) at the Queensland Institute of Medical Research, under the supervision of Dr. David McMillan. Mr Zowawi participated in the development of a novel quantitative multiplex real-time PCR assay that can be used to target common bacteria causing CRIs.

 

Research Output In The Media

 

Awards and Recognitions

Young Achiever Award, World Leadership Congress, Dubai 2015.

Queensland Science and Innovation Champion 2014, Queensland government, Australia.

Young Laureate of The Rolex Awards for Enterprise 2014.

The Saudi Ministry of Higher Education Award for Excellence in Scientific Creativity 2014.

Griffith University Award for Academic Excellence 2010.

 

100 under 40: The world’s most influential young Arabs 2016

Change Creator, The University of Queensland, 2015.

Next Generation Leader by TIME Magazine 2014.

Queensland’s top 50 Best and Brightest, The Courier Mail, 2014.

100 Most Powerful Arabs Under 40, Arabian Business, 2014.  

 

Funding Acknowledgment

Rolex Awards for Enterprise - Collaborative young laureates grant ($38,500).
Francesco Sauro, Hosam Zowawi
Support a joint expedition in South American caves to analyse microbes for novel antimicrobial compounds and understanding the evolution of antibiotic resistance

Postdoctoral Research Fellowship at UQ - Offered by The Merchant Foundation ($360,000).
Support research project at UQ aiming to develop rapid diagnosis and raise global awareness of superbugs

Australian Infectious Diseases 50:50 Sequencing Grant ($7,700).
“Whole Genome Sequencing and a validation for innovative diagnostic tools to rapidly identify antibiotic resistant bacteria”

International Society of Infectious Diseases 2014-2015 ($6,000).
Amin Aqel, Hamed Alzoubi, Hosam Zowawi, David Paterson, Timothy Walsh
“Infections caused by Gram negative bacteria in the unfortunate Syrian refugees in Jordan, epidemiological and molecular study"

Rolex Awards for Enterprise ($59,600).
“Develop faster laboratory tests for superbugs and raise awareness of antibiotic resistance in the Gulf States through an education campaign”

King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Riyadh 2011-2015 ($58,000).
Sameerah Aljohani, Hanan Balkhy, Hosam Zowawi, David Paterson, Timothy Walsh
“Surveillance of antibiotic resistant Gram negative bacilli in Saudi Arabia and the Gulf States”

Full academic scholarship from the government of Saudi Arabia.

Research Projects

Hosam is a member of the Infection and Immunity Theme, where he is studying antimicrobial resistant Gram-negative bacilli isolated from the countries of the Gulf Cooperation Council (GCC). This project will give a snapshot of the different resistance mechanisms associated with antibiotic resistant Gram-negative bacilli and will identify the predominate genotype spread in the GCC hospitals. Results generated from this project will highlight the importance of initiating active ongoing surveillance on multidrug resistance organisms in the GCC states. This project would not be possible without the collaboration of several institutes in the GCC states including:

  • King Saud bin AbdulAziz University for Health Science, National Guard-Health Affairs, Saudi Arabia
  • GCC Centre for Infection Control, National Guard-Health Affairs, Saudi Arabia
  • Department of Microbiology, Collage of Medicine, University of Dammam, Saudi Arabia
  • Kuwait University, Kuwait
  • Royal Hospital, Oman
  • Samlaniya Medical Complex, Bahrain
  • Hamad Medical Cooperation, Qatar
  • Zaid Military Hospital, United Arab of Emirates

Another interesting part of Hosam's PhD dissertation is the development of innovative diagnostic methods to rapidly identify antibiotic resistant bacteria.  Such applications will allow initial targeted treatments in the early stages of infection and will help to control the spread of antibiotic-resistant pathogens between patients.

Hosam is passionate to raise public and medical awareness about the latest in the issue of antimicrobial resistance. With the outstanding support of a multidisciplinary team, many campaigns and initiatives in different parts of the world have been launched to achieve this aim. Awareness messages are distributed by responsible science communication of published research in traditional media, effective distribution and pubic engagement through social media platforms, presenting in public events, and creating multimedia tools to raise AMR awareness.

These projects (Surveillance, Rapid diagnostics, and Educaiton) are in alignment with the Global Action Plan on Antimicrobial Resistance addressed by The World Health Organization.

Invited Presentations

The Regional Problem Caused by Antibiotic Resistant Bacteria. Invited international speaker at the 1st Gulf Congress of Clinical Microbiology and Infectious Diseases – GCCMID 2016, Dubai, UAE, 4 – 7 May 2016.

Multidrug resistant Gram-negative bacilli in the Gulf States. Invited international speaker at the 1st Gulf Congress of Clinical Microbiology and Infectious Diseases – GCCMID 2016, Dubai, UAE, 4 – 7 May 2016.

THE ULTIMATE SUPERBUG: Pandrug resistant Klebsiella pneumoniae. Invited international speaker at the 1st Gulf Congress of Clinical Microbiology and Infectious Diseases – GCCMID 2016, Dubai, UAE, 4 – 7 May 2016.

Choosing the Journal / EndNote Overview. Presented as preconference workshop at the 1st Gulf Congress of Clinical Microbiology and Infectious Diseases – GCCMID 2016, Dubai, UAE, 4 – 7 May 2016.

Writing a Research Proposal. Presented as preconference workshop at the 1st Gulf Congress of Clinical Microbiology and Infectious Diseases – GCCMID 2016, Dubai, UAE, 4 – 7 May 2016.

War on Superbugs: Fighting the Known Unknown Through a Multidisciplinary Approach. Invited Seminar at King Fahad Medical Research Center, Jeddah, 9th of April.Hosted by Dr Hani Choudhry.

Antimicrobial stewardship in the outpatient setting: educating the patients and the role of the media. Invited international speaker at the 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) / International Society of Chemotherapy (ISC)’s International Congress of Chemotherapy and Infection (ICC) - ICAAC/ICC 2015, San Diego, CA, 17 - 21 September 2015.

Invited international speaker at Every Second Count, London, 18th of November 2014. Hosted by the Guardian.

Invited international speaker at the 2014 Innovation and Entrepreneurship Forum (IE Youth), Makkah, 21st of April 2014. Hosted by Umm Al-Qura University.

Carbapenem resistant Acinetobacter baumannii and P. aeruginosa in the GCC. Invited international speaker at the 5th Saudi Critical Care Society & Society of Critical Care Medicine, Riyadh between the 15th - 17th  of April 2014.

Carbapenem resistant Enterobacteriaceae in the GCC. Invited international speaker at the 5th Saudi Critical Care Society & Society of Critical Care Medicine, Riyadh between the 15th - 17th  of April 2014.

Ventilator Associated Pneumonia (VAP) in Saudi ICUs. Invited international speaker at the 5th Saudi Critical Care Society & Society of Critical Care Medicine, Riyadh between the 15th - 17th  of April 2014.

Invited international speaker (as a fellow) at the 2014 Annual Forum of the i2 Institute for Imagination and Ingenuity, Riyadh 17th of February 2014.

How to Accurately Identify Acinetobacter baumannii?!! Case Study. Presented at the workshop of the Gram negative ‘SUPERBUG’ meeting in Brisbane, Queensland, on the 1st of August 2013. Hosted by The Australasian Society for Infectious Diseases.

The storm caused by multi-drug resistant Gram-negative bacteria in the Arabian Peninsula: clinical focus and environmental negligence. Invited speaker at the Water Desalination and Reuse Center and Environmental Science and Engineering Program of King Abdullah University for Science and Technology (KAUST), Saudi Arabia on the 17th of December 2012. Hosted by Dr. Peiying Hong.

Recent Conference Papers

Pal T, Sonnevend AM, Ghazawi A, Haidermota A, Girgis S, Alfaresi M, Omar M, Paterson DL, Beatson S, Forde B, Zowawi H. Multi-hospital spread of a pan-resistant Klebsiella pneumoniae clone with an ISEcp1-directed blaOXA-181 insertion into the mgrB gene in the United Arab Emirates. The 26th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Amsterdam, April 9-12, 2016. Oral presentation

Harris P, Zowawi H, Wailan A, Ben Zakour N, Paterson DL. Resistance phenotype prediction from whole genome sequencing data in ESBL or plasmid-AmpC-producing E. coli or K. pneumoniae: results from bloodstream isolates collected during an international multicentre randomized trial. The 26th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Amsterdam, April 9-12, 2016. Poster presentation

Zowawi HM, Syrmis MW, Kidd TJ, Balkhy HH, Walsh TR, Al Johani SM, AlJindan RY, Alfaresi M, Ibrahim E, Al-Jardani A, Al Salman J, Dashti AA, Sidjabat H, Baz O, Whiley DM, Paterson DL. Molecular Characterization of Carbapenem Resistant Pseudomonas aeruginosa in the Arabian Peninsula. The 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) / International Society of Chemotherapy (ISC)’s International Congress of Chemotherapy and Infection (ICC) - ICAAC/ICC 2015, San Diego, CA, September 17–21, 2015. Poster presentation

Harris PNA, Zowawi HM, Banu S, Paterson DL. Mapping the Global Prevalence of Resistance to Antimicrobials in Gram-negative Urinary Pathogens: A Meta-analysis of Contemporary Studies. The 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) / International Society of Chemotherapy (ISC)’s International Congress of Chemotherapy and Infection (ICC) - ICAAC/ICC 2015, San Diego, CA, September 17–21, 2015. Oral presentation

Zowawi HM, Balkhy HH, Al Johani S, Al-Jindan RY, Dashti A, Aljardani A, AlSalman J, Ibrahim E, Alfaresi M, Sidjabat H, Paterson DL. 2013. Molecular Epidemiology of Carbapenem Non-Susceptible Acinetobacter baumannii Isolates From the Gulf Cooperation Council States. Gram negative ‘SUPERBUG’ meeting, The Australasian Society for Infectious Diseases, Gold Coast, Queensland, August 2013. Poster presentation

Paterson DL, Zowawi HM, Huber C, Sidjabat H. 2013. The Accuracy of Combined Disk Assay to Screen for Metallo-ß- Lactamases in Carbapenem Resistant Acinetobacter baumannii. Gram negative ‘SUPERBUG’ meeting, The Australasian Society for Infectious Diseases, Gold Coast, Queensland, August 2013. Poster presentation

Zowawi HM, Walsh TR, Balkhy HH, Paterson DL. 2012. How Far Away is the Arabian Peninsula from the Storm Caused by "Carbapenem Resistant Gram-Negative Bacilli?" 13th Annual Scientific Meeting of the Australian Society for Antimicrobials. Brisbane, Queensland, February 2012. Oral presentation

Zowawi HM, Walsh TR, Balkhy HH, Paterson DL. 2011. Broad spectrum ß-lactamase producing Gram-negative bacilli (GNB) in the Gulf Cooperation Council (GCC) states - "The known known and the known unknown". 3rd International Conference on Infections and Tropical Diseases, 6th GCC conference on infection control. Muscat, Oman, December 2011. Poster presentation

Zowawi HM, Walsh TR, Balkhy HH, Paterson DL. 2011. Factors that may contribute in increasing the prevalence of broad spectrum ß-lactamase producers among Gram-negative bacilli in the Gulf Cooperation Council (GCC) states. 3rd International Conference on Infections and Tropical Diseases, 6th GCC conference on infection control. Muscat, Oman, December 2011. Poster presentation

Zowawi HM, Gowardman J, Rickard C, Zhang L, McMillan D. 2011. Real-Time PCR Assays for the Diagnosis of Bacterial Colonization of Catheters. 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, Illinois, September 17 - 20, 2011. Poster presentation

Published Journal Papers

Zowawi HM, Forde B, Alfaresi M, Alzarouni A, Farahat Y, Chong T, Yin W, Chan K, Li J, Schembri MA, Beatson SA, Paterson DL. Stepwise evolution of pandrug-resistance in Klebsiella pneumoniae. Sci Rep. 2015 Oct 19;5:15082.

Zowawi HM, Abedalthagafi M, Mar FA, Almalki T, Kutbi AH, Harris-Brown T, Harbarth S, Balkhy HH, Paterson DL, Hasanain RA. The Potential Role of Social Media Platforms in Community Awareness of Antibiotic Use in the Gulf Cooperation Council States: Luxury or Necessity? J Med Internet Res. 2015 Oct 15;17(10):e233.

Wailan A, Sartor A, Zowawi HM, Perry J, Paterson D, Sidjabat H. The genetic characterization of NDM-1 producing Enterobacteriaceae and Acinetobacter baumannii in patients with multiple NDM-1-producing strains for an insight of blaNDM-1 acquisition via plasmids. Antimicrob Agents Chemother. 2015 Sep 21. pii: AAC.01319-15. [Epub ahead of print]

Toh B, Paterson DL, KamolvitW, Zowawi HM, Kvaskoff D, SidjabatH, Peleg AY, Huber CA. Species identification within the Acinetobacter calcoaceticus - baumannii complex using MALDI - TOF MS. J Microbiol Methods. 2015 Sep 14;118:128-132. doi: 10.1016/j.mimet.2015.09.006. [Epub ahead of print]

Zowawi HM, Harris PNA, Roberts M, Schembri MA, Williamson D, Tambyah PA, Paterson DL. The Emerging Threat Of Multi-Drug Resistant Gram-Negative Bacteria In Urology. Nat Rev Urol. 2015 Oct;12(10):570-84.

Toh B, Zowawi HM, Krizova L, Paterson DL, Kamolvit W, Peleg A, Sidjabat H, Nemec A, Pflüger V, Huber C. Differentiation of Acinetobacter Genomic Species 13BJ/14TU from Acinetobacter haemolyticus using MALDI - TOF MS. J Clin Microbiol. 2015 Oct;53(10):3384-6.

Zowawi HM, Ibrahim E, Syrmis, MW, Wailan AM, AbdulWahab A, Paterson DL. PME-1 Producing Pseudomonas aeruginosa in Qatar. Antimicrob Agents Chemother. 2015 Jun;59(6):3692-3.

Zowawi HM, Sartor AL, Sidjabat HE, Balkhy HH, Walsh TR, Al Johani SM, AlJindan RY, Alfaresi M, Ibrahim E, Al-Jardani A, Al Salman J, Dashti AA, Johani K, Paterson DL. Molecular Epidemiology of Carbapenem Resistant Acinetobacter baumannii in the Gulf Cooperation Council States. Dominance of OXA-23-like producers. J Clin Microbiol. 2015 Mar;53(3):896-903.

Zowawi HM, Sartor AL, Balkhy HH, Walsh TR, Al Johani SM, AlJindan RY, Alfaresi M, Ibrahim E, Al-Jardani A, Al-Abri S, Al Salman J, Dashti AA, Kutbi AH, Schlebusch S, Sidjabat HE, Paterson DL. Molecular Characterization of Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae in the Countries of the Gulf Cooperation Council: Dominance of OXA-48 and NDM Producers. Antimicrob Agents Chemother. 2014 Jun;58(6):3085-3090.

Zowawi HM, Balkhy HH, Walsh TR, Paterson DL. Beta-lactamase Production in Key Gram-Negative Pathogen Isolates from the Arabian Peninsula. Clin Microbiol Rev. 2013 Jul;26(3):361-80.

 

Collaborations

GCC Centre for Infection Control, National Guard-Health Affairs, Saudi Arabia - Dr. Hanan Balkhy

Clinical Microbiology section, Pathology and Laboratory Medicine Department, King Abdulaziz Medical City, National Guard-Health Affairs, Saudi Arabia - Dr. Sameera Al-johani

Department of Microbiology, Collage of Medicine, University of Dammam, Saudi Arabia - Dr. Reem Al-Jindan

Health Sciences Centre, Kuwait University, Kuwait - Professor Ali Dashti

Clinical Microbiology department, The Royal Hospital, Oman - Dr. Amina Aljardani

Samlaniya Medical Complex, Bahrain - Dr. Jameela AlSalman, Dr. Ahmed Alalawai, Prof. Dr. Hicham Ezzat

Hamad Medical Cooperation, Doha, Qatar - Dr. Emad Elmagboul, Dr. Mamoun Elsheikh, Dr. Atqa Abdulwahab

Zaid Military Hospital, Abu Dhabi, United Arab of Emirates - Dr. Mubarak Alfaresi, Dr. Saif Albedwawi, Dr. Mohammed AlKabi

Sheikh Khalifa General Hospital, Umm Al Quwain, United Arab of Emirates - Dr. Mubarak Alfaresi, Dr. Abdulqadir Alzarouni, Dr. Yasser Farahat

King Abdullah University for Science and Technology (KAUST), Saudi Arabia - Dr. Peiying Hong

International Extended Care Centre, Saudi Arabia –Dr. Yasser Mandourah

Ain Shams University, Faculty of Medicine, Cairo, Egypt - Dr. Safaa Mohamed Abdel-Rahman, Dr. Marwa Elsayed

Hôpitaux Universitaires de Genève, Service de Prévention et Contrôle de l'Infection, Switzerland – Prof Stephan Harbarth

Mu'tah University, Faculty of Medicine, Al-Karak, Jordan - Dr. Amin A. Aqel, Dr. Hamed Alzoubi

Mater Hospital, Clinical Microbiology department, Australia - Dr. Sanmarié Schlebusch

Queensland Paediatric Infectious Diseases Laboratory, Royal Children’s Hospital, Australia – A/Prof David Whiley, Dr. Timothy Kidd, Dr. Melanie Syrmis

Harvad University, Harvard Medicical School, U.S. – Dr. Malak Abedalthagfi, Prof. John Brownstein

School of Chemistry and Molecular Biology, UQ – Prof Mark Schembri, A/Prof Scott Beatson, Dr. Brain Forde

Monash Institute of Pharmaceutical Science, Monash University, Australia – Prof Jian Li

University of Bologna, School of Engineering and Architecture, Italy – Dr. Francesco Sauro

La Venta, Italy – Dr. Francesco Sauro

Teaching

MEDI1011: Medical Microbiology offered to Medical Students

BIOC6014: Literature Review in Molecular Biology A - Postgraduate Coursework