Dr Hanna Sidjabat

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Researcher Interests

Dr. Sidjabat's research areas are:

-  Investigation of mechanisms of plasmid-mediated antimicrobial resistance genes in Gram-negative pathogens

- Replicon typing of plasmid carrying antibiotic resistance genes

- Molecular epidemiology of antibiotic resistance genes in Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae and other Gram-negative bacteria

 

- Development of simple and reliable method to characterise type of beta-lactamases

Research Projects

Complete plasmid sequencing of New Delhi Metallo-β-lactamase gene carrying plasmid

Replicon typing of plasmid carrying resistance to expanded-spectrum cephalosporins in E. coli and K. pneumoniae

Genetic environment of blaOXA-23 in Acinetobacter baumannii

Key Words

antimicrobial or antibiotic resistance, Gram-negative

Colleagues

Professor David Paterson

Dr. Benjamin Rogers (colleague and PhD student of Prof. David Paterson in studying the risk factor of infections due to O25b-ST131 E. coli and writing a review article on Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain

Dr. Yoshiro Hayashi (colleague on redefining the piperacillin minimum inhibitory concentration of Pseudomonas aeruginosa from intensive care unit)

Lyn Coleman (colleague and Master student from Griffith University in studying the use of boronic acid on AmpC detection in Escherichia coli and Klebsiella pneumoniae)

Dr. Marjoree Sehu (colleague and Microbiology Registrar at the Queensland Pathology Microbiology Central Laboratory in studying the occurrence of metallo-β-lactamases in Pseudomonas aeruginosa)

Professor Matthew Cooper (NHMRC Australia Fellow) in conducting mouse trial for in vivo testing of new modified vancomycin compounds

Collaborations

Yohei Doi, MD, PhD (Division of Infectious Diseases - University of Pittsburgh) in studying the complete plasmid sequencing of KPC-carrying plasmids

Dr. Graeme R. Nimmo (Director of Queensland Pathology Microbiology Central Laboratory) in studying the resistance mechanisms in Gram-negative bacteria

Robyn Carter (Queensland Pathology - Mycobacterium Reference Laboratory) and Dr. Henry Marshall (Prince Charles Hospital) in studying the clonal relationship analysis in Mycobacterium fortuitum and Mycobacterium lentiflavum using Diversilab rep-PCR

Research  Associate

Anna Silvey, PhD - Researcher

Key Publications

Sidjabat, H., Nimmo, G.R., Walsh, T.R., Binotto, E., Htin, A., Hayashi, Y., Li, J., Nation R.L., George, N. and Paterson, D.L. 2011. Carbapenem resistance in Klebsiella pneumoniae due to the New Delhi Metallo-β-lactamase. Clin Infect Dis. 52:481-4.

Marshall, H.M., Carter, R., Torbey, M.J., Minion, S., Tolson, C., Sidjabat, H.E., Huygens, F., Hargreaves, M, Thomson, R.M. 2011. Mycobacterium lentiflavum in drinking water supplies, Australia. Emerg Infect Dis. 17:395-402.

Waltner-Toews, R.I., Paterson, D.L., Qureshi, Z.A., Sidjabat, H.E., Adams-Haduch, J.M, Shutt, K.A., Jones, M., Tian, G.B., Pasculle, A.W. and Doi, Y. 2011. Clinical characteristics of bloodstream infections due to ampicillin/sulbactam-resistant, Non-ESBL-producing Escherichia coli and the role of TEM-1 hyperproduction. Antimicrob Agents Chemother. 55:495-501.

Rogers, B.A., Sidjabat, H.E. and Paterson, D.L. 2010. Escherichia coli O25b-ST131: a pandemic multiresistant, community-associated strain. J Antimicrob Chemother. 66:1-14.

Runnegar, N., Sidjabat, H., Goh, H.M., Nimmo, G.R., Schembri, M.A., Paterson, D.L. 2010. Molecular epidemiology of multidrug-resistant Acinetobacter baumannii in a single institution over a 10-year period. J Clin Microbiol. 48:4051-6.

 

Contact details and email

Hanna E. Sidjabat

The University of Queensland, Building 71/918 RBWH Herston QLD 4029

Telephone: (07) 3346 6082

Facsimile: (07) 3346 5598

Email: h.sidjabat@uq.edu.au